How to clean urine from a memory foam mattress

Dealing with urine stains and odors on a memory foam mattress can be a frustrating and unpleasant experience. However, with the right techniques and products, it’s possible to effectively remove urine from your mattress and restore its fresh, clean condition. In this comprehensive guide, we’ll walk you through the step-by-step process of cleaning urine from a memory foam mattress, providing you with practical tips and tricks to ensure successful stain and odor removal.

clean urine from a memory foam mattress

The Challenge of Cleaning Urine from Memory Foam

Memory foam mattresses are designed to conform to the shape of your body, providing superior comfort and support. However, this unique construction also makes them more challenging to clean when it comes to urine stains and odors. Unlike traditional mattresses with an absorbent top layer, memory foam mattresses are dense and can trap liquids deep within their structure.

When urine seeps into the memory foam, it can quickly lead to unpleasant odors and potential bacterial growth. Additionally, the porous nature of memory foam can make it difficult to fully remove all traces of urine, leading to lingering smells and stains if not properly addressed.

Urine AbsorptionMemory foam’s dense structure can trap urine deep within the mattress.
Odor DevelopmentTrapped urine can lead to unpleasant odors and potential bacterial growth.
Stain PersistenceThe porous nature of memory foam makes it harder to fully remove urine stains.

Preparation: Gathering the Right Supplies

Before you start the cleaning process, it’s essential to gather the necessary supplies. Here’s what you’ll need:

  1. Absorbent materials (paper towels, clean rags, or a wet/dry vacuum)
  2. Enzyme-based cleaner (specifically designed for urine removal)
  3. White vinegar (for neutralizing odors)
  4. Baking soda (for absorbing moisture and odors)
  5. Clean towels or cloths
  6. Protective gloves (optional)

Step 1: Act Quickly to Soak Up Fresh Urine

Time is of the essence when dealing with urine stains on a memory foam mattress. The sooner you attend to the stain, the easier it will be to remove. As soon as you notice the urine spill, use absorbent materials like paper towels or clean rags to soak up as much of the liquid as possible.

If the urine has already soaked deep into the mattress, consider using a wet/dry vacuum to extract as much moisture as possible from the surface and interior of the memory foam. This initial step is crucial to prevent the urine from setting deeper into the mattress and minimizing the potential for odors and stains.

Step 2: Apply an Enzyme-Based Cleaner

Once you’ve soaked up as much urine as possible, it’s time to tackle any remaining stains and odors with an enzyme-based cleaner specifically designed for urine removal. These cleaners contain enzymes that break down the proteins and acids found in urine, effectively eliminating stains and odors at their source.

Follow the manufacturer’s instructions for dilution and application. Typically, you’ll need to spray or pour the enzyme cleaner directly onto the affected area and allow it to sit for a specified amount of time (usually 10-15 minutes) to work its magic.

Pro Tip: For stubborn stains, make a paste by mixing the enzyme cleaner with a small amount of water and applying it directly to the affected area. Let it sit for 30 minutes before blotting and rinsing.

Step 3: Blot and Extract Excess Moisture

After the enzyme cleaner has had time to work, use clean towels or cloths to blot and absorb any excess moisture from the mattress surface. Apply firm pressure to help extract as much liquid as possible from the memory foam.

If the stain is particularly stubborn or has penetrated deep into the mattress, you may need to repeat the process of applying the enzyme cleaner, letting it sit, and blotting until the stain and odor are completely gone.

Important Note: Avoid rubbing or scrubbing the stain, as this can push the urine further into the memory foam and make it harder to remove.

Step 4: Neutralize Odors with White Vinegar

Even after thorough cleaning, lingering urine odors can persist in memory foam mattresses. To combat this issue, white vinegar can be an effective natural odor neutralizer. Mix equal parts of white vinegar and water in a spray bottle, and generously mist the affected area with the solution.

Allow the vinegar solution to sit for a few minutes, then blot the area with clean towels or cloths to absorb any excess moisture. The acidic properties of vinegar will help break down any remaining urine compounds, eliminating unpleasant odors from the memory foam.

Tip: For extra deodorizing power, add a few drops of essential oils like lemon or eucalyptus to the vinegar solution.

Step 5: Deodorize with Baking Soda

Baking soda is another powerful weapon in the fight against urine odors in memory foam mattresses. After applying the vinegar solution, sprinkle a generous amount of baking soda over the affected area. Baking soda is a natural absorbent and deodorizer, and it will help draw out any remaining moisture and odors from the mattress.

Leave the baking soda on the mattress for several hours or overnight, allowing it ample time to work its magic. The longer you leave it, the more effective it will be in eliminating odors.

Additional Suggestion: For maximum odor absorption, mix the baking soda with a few drops of essential oils like lavender or tea tree before sprinkling it on the mattress.

Step 6: Vacuum and Fluff the Mattress

Once the baking soda has had time to work, use a vacuum cleaner with a hose attachment to remove any remaining powder from the mattress surface. Be sure to vacuum thoroughly to ensure no baking soda residue is left behind.

After vacuuming, fluff the memory foam mattress by kneading and pressing down on it with your hands or a clean towel. This will help restore the mattress’s shape and allow any trapped air to circulate, further facilitating the drying process and dissipating any lingering odors.

Step 7: Allow the Mattress to Fully Dry

Patience is key when it comes to allowing the memory foam mattress to fully dry after the cleaning process. Depending on the severity of the urine stain and the amount of moisture involved, it may take several hours or even a full day for the mattress to completely dry.

During this drying period, it’s essential to keep the mattress in a well-ventilated area and avoid covering it with sheets or bedding. You can also use fans or a dehumidifier to help speed up the drying process.

Expert Advice: To ensure thorough drying, consider flipping the mattress and repeating the cleaning process on the other side, as urine can sometimes seep through to the underside.

Additional Tips and Considerations

  1. Act promptly: The sooner you address a urine stain on a memory foam mattress, the better. Don’t let it sit and set into the material, as this will make it harder to remove.
  2. Test for colorfastness: Before applying any cleaning solutions, test them on a small, inconspicuous area of the mattress to ensure they won’t cause discoloration or damage.
  3. Protect the mattress: Consider investing in a high-quality mattress protector to safeguard your memory foam mattress from future accidents and spills.
    • Check out these top-rated mattress protectors: SafeRest, SureGuard
  4. Address the source: If the urine stain is the result of a pet accident or incontinence issue, it’s important to address the underlying cause to prevent future incidents.
    • For pets, consider training aids like Pett Potty Park or consulting a professional trainer.
    • For incontinence, speak with a healthcare provider about management options.
  5. Replace if necessary: In severe cases where the urine stain and odor persist despite thorough cleaning efforts, it may be necessary to replace the memory foam mattress altogether.
    • Look for high-quality memory foam mattresses from reputable brands like Tempur-Pedic or Casper.


Cleaning urine from a memory foam mattress can be a challenging task, but with the right techniques and products, it is possible to restore your mattress to a fresh, clean condition. By following the step-by-step guide outlined in this article, you can effectively remove urine stains and odors, ensuring a more comfortable and hygienic sleeping environment.

Remember, prompt action, the use of enzyme-based cleaners, and the application of deodorizing agents like vinegar and baking soda are key to successfully tackling urine stains and odors in memory foam mattresses. With patience and persistence, you can overcome this unpleasant issue and enjoy a clean, odor-free mattress once again.

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As the founder of Clean It Spotless, I am Melissa Walker, a leading expert in removing tough stains from fabrics, carpets, and upholstery. With over 10 years of experience in the cleaning industry, I have developed my own natural, non-toxic stain-fighting formulas that lift stains while preserving the integrity of the underlying material. My stain removal tutorials are widely read online, and I have appeared on local TV segments demonstrating my techniques. I also present popular stain removal workshops at community centers and schools.